Laboratory of NMR

Contact: 1111 Budapest, Szt. Gellért tér 4. fszt. 15-16.
Website: link
Focal points and main thrusts of research: Organic chemistry
Egyéb: structure investigation of organic compounds
NMR service for the collegues of the faculty and for companies (on the basis of a contract). Structure elucidation/investigation of the measured probes (in a limited quantity). National (University of Szeged) and international (Hacettepe University, Ankara, Turkey) cooperation on the field of the structure investigation of natural and biological active compounds (eg.: ecdysteroids, triterpenes, flavanoids). Laboratory practice for students.
Sample publications:

G. Varró, P. Pálchuber, B. Pogrányi, A. Simon, L. Hegedűs, I. Kádas: (±)-trans-dihydronarciclasine and (±)-trans-dihydrolycoricidine analogues modified in their ring A: Evaluation of their anticancer activity and a SAR study

       Eur. J. Med. Chem. 173, 76-89 (2019) (

M. Bojtár, A. Simon, P. Bombicz, I. Bitter: Expanding the Pillararene Chemistry: Synthesis and Application of a 10 + 1 Functionalized Pillar[5]arene

Org. Lett. 19, 4528-4531 (2017) DOI: 10.1021/acs.orglett.7b02092

A. Hunyadi, I. Herke, K. Veres, A. Erdei, A. Simon, G. Tóth: Volatile Glycosides from the Leaves of Morus alba with a Potential Contribution to the Complex Anti-diabetic Activity

Natural Product Communications 9 (2), 145-147 (2014)

G. Szántó, L. Hegedűs, L. Mattyasovszky, A. Simon, Á. Simon, I. Bitter, G. Tóth, L. Tőke, I. Kádas: An expedient total synthesis of ent-(–)-7-deoxy-trans-dihydronarciclasine

Tetrahedron 65, 8412-8417 (2009)

A. Ványolós, A. Simon, G. Tóth, L. Polgár, Z. Kele, A. Ilku, P. Mátyus, M. Báthori: C-29 Ecdysteroids from Ajuga reptans var. reptans

J. Nat. Prod. 72, 929-932 (2009)

V. Csokai, A. Grün, B. Balázs, A. Simon, G. Tóth, I. Bitter: Functionalized thiacalix- and calyx[4]arene based Ag+ ionophores: synthesis and comparative NMR study

Tetrahedron 62, 10215-10222 (2006)

S. Moeller, D. Albert, H. Duddeck, A. Simon, G. Tóth, O. M. Demchuk, K. M. Pietrusiewicz: Chiral atropisomeric diiodobiphenyls – enantiodifferentiation by the dirhodium method

Tetrahedron: Asymmetry 15, 3609-3616 (2004)

H. Duddeck, G. Tóth, A. Simon: 17O NMR Parameters

Landolt-Börnstein New Series III/35E, 2002, ISBN 3-540-42501-2, Springer Verlag, Berlin Heidelberg New York

H. S. M. Soliman, A. Simon, G. Tóth, H. Duddeck: Identification and Structure Determination of Four Triterpene Saponins from some Middle-East Plants

Magn. Reson. Chem. 39, 567-576 (2001)

Awards and achievements:
Guest professors:
Group leader: Dr. Simon András