BME Vegyészmérnöki és Biomérnöki Kar

Nyomtatás

Bioinformatics II (Lc+Pr)

BMEVESZM103

The subject gives an overview on practical methods in boinformatics with special emphasis on proteomics and problem solving capabilities related to structure-function relationship issues for bioengineers and chemical engineers in chemical and bioindustries (pharma, fine chemicals, food and cosmetics industries). Partially based on the topics of Bioinformatics 1 (put more emphasis on Genomics and algorithms) the lecture part of this subject covers the theoretical aspects of proteomics and gives insight into practical aspects of bioinformatics - proteomics by a computation practice. Short syllabus of the subject:

  • - sequence analysis - nucleotide and protein sequences, pairwise and multiple alignments of sequences, phylogenetic analysis, secundary structure prediction, domain analysis, sequence bases function prediction;
  • - protein structure related issues - 3D structure and factors for its formation and stabilization, experimental methods to determine 3D structure of proteins, 3D structure modelling methods for proteins, protein - ligand and protein - protein interactions, dinamics of proteins;
  • - relationship of genetic and structural data with molecular function and metabolic role;
  • - databases (nucleotide and protein sequence databases, structure databases, protein function related databases) - programs and interactive databases for bioinformatics - examples of practical applications of bioinformatics